Successful M&A isn’t just about closing the deal—it's about realizing its full potential.
In pharma, where integrations face unique scientific, regulatory, and commercial challenges, even high-potential deals can quickly lose momentum. Misaligned pipelines or technologies, inefficient organizational structures, and the loss of critical talent often derail value creation.
Developing a robust Post-Merger Integration (PMI) framework is essential to unlocking synergies and maximizing long-term value
Larka's M&A practice delivers custom and holistic PMI strategies that mitigate risk, accelerate synergies, and build long-term capabilities—transforming acquisitions into a catalyst for sustained growth.
- Combining our deep M&A and pharma expertise with a data-driven, tailored approach, we help our
clients achieve the four critical goals of a successful integration:
- Unlock synergies and maximize value creation.
- Maintain business momentum while executing the integration.
- Align structures, capabilities, teams, and culture to create a strong, unified organization.
- Leverage combined strengths to enhance long-term market positioning.
PMI solutions, tailored to each client’s unique needs.
Our approach to PMI.
We know no two integrations are alike. But after hundreds of PMI projects across Private Equity, Pharma, and Service Providers, we have crafted a proven framework to drive successful, value-maximizing integrations.
- Establish clear objectives aligned with the deal's value drivers.
- Treat PMI as a dedicated, structured program—regardless of deal size.
- Build cross-functional teams with leaders from both organizations.
- Ensure senior leadership is engaged, visible, and committed to success.
- Move fast. Optimize business plan & design the future organization within 3-months after closing.
- Pursue cost and revenue synergies while minimizing disruption.
- Build cross-functional teams with leaders from both organizations.
- Ensure senior leadership is engaged, visible, and committed to success.
- Define the long-term operating model beyond Day 1 execution.
- Select, retain, and integrate top talent to drive future success.
- Manage cultural alignment proactively, ensuring smooth team integration.
- Transparent, continuous communication to align teams, investors, and customers.
Beyond these key success factors, we empower clients with our proprietary integration toolkit, designed to accelerate and de-risk the PMI process:
- Synergy Database – Drawing from hundreds of PMI projects, our benchmarking tool assesses, quantifies, and validates potential synergies with precision.
- Day-One Integration Checklist – A structured, function-specific roadmap ensuring seamless business continuity and operational stability from day one.
- Culture Diagnostic Survey – Analyses organizational behaviours across both entities to anticipate challenges, align teams, and accelerate integration.
Trusted insights. Proven results.
- 300+
- Buy-side, sell-side M&A transactions and PMI projects supported
- 30%
- Greater cost and revenue synergies than other pharma-related deals
- 10%
- Higher indexed shareholder returns achieved
Let's give you the edge.
Unmatched pharma knowledge
With 30+ years of scientific and M&A transactions experience, a global network of senior-level experts and end-to-end value/supply chain expertise, Larka is a trusted partner for PMI in the pharma sector.
Proprietary Integration Toolkit
Our PMI workstreams leverage AI-powered automation and advanced analytics with proprietary data to track synergies, streamline operations, and ensure efficient execution.
Tailored Integration Strategies
Each integration is unique. Our M&A specialists build on insights from 100+ prior integrations to design custom roadmaps that align structures, processes, and cultures to maximize synergies and long-term success.
Global Expert Network
We collaborate with 500+ senior executives, scientists, KOL and industry leaders across R&D, manufacturing, regulatory, and commercial functions, providing expert-driven integration strategies tailored to the pharma ecosystem.
Corporate strategy resources
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Get in touch with our experts in post-merger integration